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26 May 2022

API development: Common Methodologies for Similar API’s Synthesis

Department of Chemistry, School of Applied Sciences, REVA University, Bangalore, Organized Virtual webinar entitled "API development: Common Methodologies for Similar API’s Synthesison May 26th, 2022, from 09:30 AM to 10.30 AM as a part of the knowledge sharing program for the benefit of students.

Resource person:
Dr. Rao Venkataramana Rao Ph. D
CVR Life Sciences, MN-Park/IKP, Shamirpet, Hyderabad
Mobile: 770-292-3131;

Dr. Madhusudana Reddy M B and
Dr. Nagendra G
Department of Chemistry, SoAS,
REVA University, Bangalore.

Dr Rao Venkataramana Rao is the Deputy General Manager of CVR Life Sciences. Dr Rao Venkataramana Rao has 21 years of research experience working in various prestigious academic institutions and pharmaceutical industries. Dr Rao Venkataramana Rao has several patents and publications in peer reviewed journals.

Dr. Rao Venkataramana Rao completed his Ph.D from Bangalore University moved to University of Arizona to work with Prof Eugene A Mash for his postdoctoral research. He was then promoted to Research Associate wherein he worked on new coupling reactions with Prof. Dominic V McGrath. After completing his tenure in USA, Dr. Rao Venkataramana Rao moved to India, worked at COSMIC Discoveries, Dr. Reddy's Institute of Life Sciences, Piramal Health Care and Ritvis Labs.

As Deputy General Manager at CVR life sciences, Dr Rao Venkataramana Rao plays a significant role in API design and development. His main research focus is to develop methodologies which can be applied to multiple API synthesis. He has successfully implemented novel methodologies in API synthesis.

 Dr. Rao Venkataramana Rao is Scientific advisory member to Journal of Organic Chemistry: Process Development (JOCPD) and International

Journal of Organic Chemistry (IJOC) and corporate Advisory Member at Dept. of Chemistry, REVA university, Bangalore. He has invited as a resource person to various institutes in India and he delivered invited talks and presented his view on new IPS’s structure of synthesis.

Highlights of the talk

  • Synthesis of API’s on gram scale using literature procedure for polymorph study as well as modified synthetic routes.
    Design of synthetic routes and execution of target compounds on CRO model.
  • Development and scale up novel and non-infringing processes for drug candidates and demonstration on kilo scale.

Selection of route for the synthesis of following API’s

  • Eliglustat
  • Droxidopa synthesis
  • Jos Barluenga coupling reactions and its applications
  • Ceretinib
  • Abiraterone
  • Olmesartan
  • Escilatopram
  • Citalopram
  • Cost reduction in the APIs synthesis

The lecture was attended by all PG students, research scholars and faculty of chemistry REVA University and other places. A total of 88 participants attended the live webinar and the feedback given by the participants was appreciated.

We would like to thank, Dr. Rao Venkataramana Rao for delivering the talk and participants, faculty members of chemistry department. We also thank Assistant Director, Department Chemistry, Deputy Director, and management for constant support and encouragement towards academic activities of the school.

Dr. Nagendra G,
Associate Professor,
Department of Chemistry, SoAs
REVA University, Bangalore.
Webinar Link: Click here