School of Applied Sciences
Physical Chemistry and Computational Chemistry
Ph.D: University of Calcutta
2017
5.5 years
|
Name of the Principal Investigator/ Co-Investigator (if applicable) |
Name of the Funding agency |
Type (Government/Non-Government) |
Department |
Year of Award |
Funds provided (INR in lakhs) |
Year Of Sanction |
Status |
|
1 (Co-PI) |
CSIR |
Government |
MBU,IISc |
2018 |
21 |
2018 |
Completed |
|
2 (Co-PI) |
UGC |
Government |
MBU, IISc |
2018 |
27 |
2018 |
Completed |
Key Publications
1. Halder, S; Surolia, A and Mukhopadhyay, C. Impact of glycosylation on stability, structure and
unfolding of soybean agglutinin (SBA): an insight from thermal perturbation molecular dynamicssimulations. Glycoconj J.2015, DOI 10.1007/s10719-015-9601-y.
2. Halder, S; Surolia, A and Mukhopadhyay, C. Dynamics simulation of soybean agglutinin (SBA) dimer reveals the impact of glycosylation on its enhanced structural stability. Carbohydrate Research.2016, 428, 8–17.
3. Halder, S and Mukhopadhyay, C. Effect of glycosylation on hydration behavior at the Ice-Binding Surface of the Oceanpout type III Antifreeze Protein: A molecular dynamics simulation. Journal of Molecular Structure and Dynamics.2016, DOI 10.1080/07391102.2016.1264888.
4. Kumar,P; Halder,S and Bansal,M. BiomolecularStructures:Prediction,Identification and Analyses.Elsevier. 2019.
5. Halder, S; Bansal, M. The effect of mutation in the stem of MicroROSE RNA thermometer on its thermosensingability and gene expression:Insightsfrom molecular dynamics simulation studies. RSC Advances. 2022, 12, 11853-11865
My research focuses on computational simulations on glycosylated proteins and nucleic acid systems to get better insight into structural variables and protein-nucleic acid interactions. It employs several advanced simulations techniques to understand the complex behaviour of the biological systems and catalysis of enzymes.
